Listed are Studies supported by InCROM since 2015
(majority conducted at Heishinkai Medical Corporation sites)

Year Therapeutic Area Phase Population No. of
Subjects
(Site)		 No. of
Subjects
(Protocol
Total)		 No. of
Visit		 Study
Duration		 Study
Site
2024 COVID-19 III Healthy males and females over 18 years of age 293 2,000
(Multi Site)		 6 365 days OPHAC Hospital
2024 COVID-19 III Healthy males and females over 18 years of age 273 2,000
(Multi Site)		 6 365 days OCROM Clinic
2024 COVID-19 III Healthy males and females over 18 years of age 234 2,000
(Multi Site)		 6 365 days ToCROM Clinic
2023 COVID-19 III Healthy males and females over 18 years of age 312 2,000
(Multi Site)		 7 365 days OPHAC Hospital
2023 COVID-19 III Healthy males and females over 18 years of age 200 2,000
(Multi Site)		 7 365 days OCROM Clinic
2023 COVID-19 III Healthy males and females over 18 years of age 288 2,000
(Multi Site)		 7 365 days ToCROM Clinic
2023 COVID-19 III Healthy males and females over 18 years of age 61 850
(Multi Site)		 5 181 days OPHAC Hospital
2023 COVID-19 III Healthy males and females over 18 years of age 74 850
(Multi Site)		 5 181 days OCROM Clinic
2023 COVID-19 III Healthy males and females over 18 years of age 71 850
(Multi Site)		 5 181 days ToCROM Clinic
2023 COVID-19 I / II Males and females 18 to 64 years of age
and eldarly males and females 65 to 75 years of age		 Part 1 : 96
Part 2 : 108		 396
(Multi Site)		 Part 1 : 9
Part 2 : 8		 365 days OPHAC Hospital
2023 COVID-19 I / II Males and females 18 to 64 years of age
and eldarly males and females 65 to 75 years of age		 109 396
(Multi Site)		 9 365 days OCROM Clinic
2023 COVID-19 I / II Males and females 18 to 64 years of age
and eldarly males and females 65 to 75 years of age		 106 396
(Multi Site)		 9 365 days ToCROM Clinic
2023 COVID-19 III Healthy males and females over 18 years of age 100 780
(Multi Site)		 6 361 days OPHAC Hospital
2023 COVID-19 III Healthy males and females over 18 years of age 110 780
(Multi Site)		 6 361 days ToCROM Clinic
2023 COVID-19 III Healthy males and females 12 to 17 years of age 5 450
(Multi Site)		 6 393 days OPHAC Hospital
2023 COVID-19 III Healthy males and females 12 to 17 years of age 5 450
(Multi Site)		 6 393 days ToCROM Clinic
2022 Pneumococcal Conjugate III Eldarly males and females over 65 years of age 70 440
(Multi Site)		 2 30 days OPHAC Hospital
2022 Pneumococcal Conjugate III Eldarly males and females over 65 years of age 70 440
(Multi Site)		 2 30 days OCROM Clinic
2022 Pneumococcal Conjugate III Eldarly males and females over 65 years of age 70 440
(Multi Site)		 2 30 days ToCROM Clinic
2022 COVID-19 II Males and females 18 to 55 years of age
and eldarly males and females over 65 years of age		 55 (18 to 55 years of age)
55 (over 65 years of age)		 300
(Multi Site)		 9 365 days OPHAC Hospital
2022 COVID-19 III Healthy males and females 18 to 40 years of age 40 1,500
(Global / Multi Site)		 10 483 days OCROM Clinic
2022 Others I Healty males and females 20 to 64 years of age 20 20 7 120 days OPHAC Hospital
2022 COVID-19 I Males and females 18 to 55 years of age
and eldarly males and females over 65 years of age		 46 (18 to 55 years of age)
46 (over 65 years of age)		 92 9 365 days OPHAC Hospital
2021 COVID-19 I / II Males and females over 18 years of age 115 2,000
(Multi Site)		 8 503 days OPHAC Hospital
2021 COVID-19 I / II Males and females over 18 years of age 115 2,000
(Multi Site)		 8 503 days OCROM Clinic
2021 COVID-19 I / II Males and females over 18 years of age 190 2,000
(Multi Site)		 8 503 days ToCROM Clinic
2021 Respiratory Syncytial III Eldarly males and females over 60 years of age 50 30,000
(Global / Multi Site)		 4 – OPHAC Hospital
2021 COVID-19 I / II Males and females over 20 years of age 32 145
(Multi Site)		 8 386 days OPHAC Hospital
2021 COVID-19 I / II Males and females over 20 years of age 44 145
(Multi Site)		 8 386 days OCROM Clinic
2021 COVID-19 I / II Males and females over 20 years of age 51 145
(Multi Site)		 8 386 days ToCROM Clinic
2021 COVID-19 I / II Healty males and females 18 to 65 years of age 57 240
(Multi Site)		 12 (including hospitalisation) 394days OPHAC Hospital
2021 COVID-19 I / II Healty males and females 18 to 65 years of age 115 240
(Multi Site)		 9 394days ToCROM Clinic
2021 COVID-19 I / II Males and females over 18 years of age 91 400
(Multi Site)		 11 365days OPHAC Hospital
2021 COVID-19 I / II Males and females over 18 years of age 79 400
(Multi Site)		 11 365days OCROM Clinic
2021 COVID-19 I / II Males and females over 18 years of age 63 400
(Multi Site)		 11 365days ToCROM Clinic
2021 Pneumococcal conjugate III Eldarly males and females over 60 years of age 70 400
(Multi Site)		 3 56days OPHAC Hospital
2021 Pneumococcal conjugate III Eldarly males and females over 60 years of age 146 400
(Multi Site)		 3 56days OCROM Clinic
2021 Pneumococcal conjugate III Eldarly males and females over 60 years of age 136 400
(Multi Site)		 3 56days ToCROM Clinic
2020 COVID-19 I / II Males and females 20 to 64 years of age 60（Ph1） 214
(Multi Site)		 13 386 days OPHAC Hospital
2020 COVID-19 II / III Males and females over 18 years of age 80 500
(Multi Site)		 7 365 days OPHAC Hospital
2020 COVID-19 II / III Males and females over 18 years of age 90 500
(Multi Site)		 7 365 days OCROM Clinic
2020 COVID-19 II / III Males and females over 18 years of age 80 500
(Multi Site)		 7 365 days ToCROM Clinic
2020 Influenza III Males and females over 60 years of age 320 2,100
(Multi Site）		 2 28 days OPHAC Hospital
2020 Influenza III Males and females over 60 years of age 350 2,100
(Multi Site)		 2 28 days OCROM Clinic
2020 Influenza III Males and females over 60 years of age 350 2,100
(Multi Site)		 2 28 days ToCROM Clinic
2020 Influenza III Males and females over 60 years of age 180 2,100
(Multi Site)		 2 28 days Other Medical Iinstitutions
2020 Others III Healthy males 20 to 45 years of age 100 900
(Multi Site)		 10 42 days OPHAC Hospital
2020 Others I Healty males and females 10 to 54 years of age 214 360
(Multi Site)		 2 30 days ToCROM Clinic
2020 Others I Healty males and females 10 to 54 years of age 106 360
(Multi Site)		 2 30 days Other Medical Iinstitutions
2018 Others I Healty males 20 to 39 years of age 60 60 2 43 days OPHAC Hospital
2018 Influenza III Healty males and females 13 to 64 years of age 215 (under 19 of age)
535 (over 20years of age)		 1,500
(Multi Site)		 3 180 days OPHAC Hospital
2019 Others III Healthy eldarly males and females over 65 years of age 50 240
(Multi Site)		 2 30 days OPHAC Hospital
2017 Influenza II Males and females over 13 years of age 50 (13 to 19 years of age)
100 (20 to 64years of age)
100 (over 65years of age)		 500
(Multi Site)		 5 180 days OPHAC Hospital
2017 Influenza II Males and females over 13 years of age 50 (13 to 19 years of age)
100 (20 to 64years of age)
100 (over 65years of age)		 500
(Multi Site)		 5 180 days ToCROM Clinic
2017 Influenza I / II Eldarly males and females over 65 years of age 85 175
(Multi Site)		 3 28 days OCROM Clinic
2017 Influenza I / II Eldarly males and females over 65 years of age 90 175
(Multi Site)		 3 28 days ToCROM Clinic
2016 Influenza I Healthy males 20 to 49 years of age 90 90 1 nt 2 days x 2 + 5 visits 56 days OPHAC Hospital
2016 Influenza II Healty males and females 20 to 64 years of age 300 600
(Multi Site)		 3 43 days(180 days) OPHAC Hospital
2016 Influenza I Healty males 20 to 39 years of age
and eldarly males and females over 65 years of age		 60 (20 to 39 years of age)
60 (over 65years of age)		 120 5 180 days OPHAC Hospital
2015 Influenza I Healty males and females 20 to 64 years of age 120 120 7 21 days(180 days) OPHAC Hospital